What’s on my mind this month is the importance of planning for the future, whether it is in our own lives or for the betterment of others.
The month of May marks an important step in the lives of our senior medical, graduate and allied health students: commencement. All of our graduating class will be transitioning into the next phase of their careers. For some, it means a residency and additional years of specialized medical training. For others, it is a postdoctoral fellowship and an opportunity to explore a new area of biomedical research. For a few students, it is a first job and a chance to implement the education they’ve received at the School of Medicine in the real world. Whatever their path may be, all our graduating students are facing their personal futures.
This month we also held a School of Medicine-wide research strategy forum to discuss the future of our biomedical research portfolio, which is, once again, facing a tenuous outlook. We’ve just come from a time where the future of science looked bright. The American Recovery and Reinvestment Act of 2009 spurred on new projects, many of which were initiated at the School of Medicine. In addition, the BRAIN Initiative, the Precision Medicine Initiative and the Cancer Moonshot clearly demonstrated that public support of research was alive and well. Indeed, the great need to stabilize the NIH’s budget was brought to the fore by the passing of the 21st Century Cures Act in 2016.
However, the hope that these programs has cultivated over the last years has been thwarted by the long-lasting effects of the 2008 financial crisis and Sequestration in 2013. Now, we face a new challenge threatening to set the biomedical research community back once again: the proposed cuts to the NIH’s budget. The half-day research strategy forum was intended to help us plan for the future of our research, not only for the sake of the dynamic and innovative projects ongoing at the School of Medicine, but for the countless patients’ lives which are saved because of the work we do here every day.
In this month’s issue of the SOMnews, we address another type of future—our children. As an academic medical school with clinical care as a key mission area, we have a great responsibility to enhance the health and wellbeing of children and adolescents. From managing a healthy pregnancy, to a healthy birth, to a healthy childhood, our faculty physicians and clinical practice staff have a key role in ensuring that the children whose lives we impact will become adults who contribute positively to the good of our society. To the extent that we can provide very best care, we are investing in our future.
Indeed, the World Health Organization measures a country’s prosperity and development status on the health of the infants and children within it. Despite progress in maternal and perinatal care, in the United States, which has some of the most advanced health care available, approximately 6 deaths per 1,000 live births occur annually, and we rank 44th for infant mortality in world. As a nation, we’ve not been good investors in our children’s future.
However, over the course of our 210-year history, the School of Medicine has made an indelible impact on children’s health. In 1867, University of Maryland School of Medicine was the first in America to appoint a chair of diseases of women and children, recognizing the importance of gynecology and pediatrics as disciplines. Dr. James Rowland, a School of Medicine graduate and dean from 1916-1940, championed better obstetrical care for women living in Baltimore’s inner city. Dr. Ruth Baldwin, a School of Medicine alumna, was the co-discoverer of the causes of congenital cerebromacular degeneration, which causes children to lose their sight at age 6 or 7. In 1980, the Sudden Infant Death Syndrome (SIDS) Institute opened, which was the first in the Nation to combine education, research and patient care into a comprehensive study to combat “crib death.”
Today, we continue our legacy in providing the very best care for all our patients over the entire course of their lives. We have a robust children’s faculty practice, which not only includes general pediatrics but pediatric surgery. Our Dean’s Surgical Council, introduced several years ago, brings together surgeons for children’s services into a single group dedicated to collaborative care. As a school which practices discovery-based medicine, the care we provide our pediatric patients is greatly impacted by our research—from research aimed to uncover and treat developmental birth defects, to pediatric cardiac stem cell research, to metabolic disorders that affect young children and teenagers.
As we look toward our future, and to that of the youngest and most vulnerable among us, I strongly encourage you to recommit yourselves to the high level of scholarship and achievement that has set us apart for the last two centuries. Our ultimate goals are to advance health and cure disease. The faculty physicians in children’s health services are working assiduously to accomplish those goals. I am supremely confident that we can continue on this extraordinary trajectory, ushering in a healthier generation to the Third Century.
Sincerely yours,
E. Albert Reece, MD, PhD, MBA
Vice President for Medical Affairs, University of Maryland
John Z. and Akiko K. Bowers Distinguished Professor and
Dean, University of Maryland School of Medicine
We welcome our new faculty and staff!
Li-Qun (Larry) Zhang, PhD joined the Department of Physical Therapy & Rehabilitation Science (PTRS) on April 17 as a tenured Professor, with secondary joint appointments in the Department of Orthopaedics at the School of Medicine and the Department of Bioengineering at University of Maryland, College Park. Dr. Zhang comes to PTRS from the Rehabilitation Institute of Chicago and Northwestern University, and brings NIDILRR and NIH SBIR grant support for robotic rehabilitation, where he has an extensive track record in rehabilitation engineering applications in multiple clinical populations.
Kudos to our colleagues who are experts in their fields and give their all to represent the School of Medicine!
Maureen Black, PhD, the John A. Scholl, MD and Mary Louise Scholl, MD Professor in Pediatrics, was invited to be a visiting professor at the University of Massachusetts, Amherst where she presented the Tay Gavin Erickson Lecture on “Building Blocks: Promoting Healthy Habits Through Childcare” on March 2. She also was invited to give a talk at the Dart Center of Journalism, Columbia University. New York City, NY, on “Returns on Investment: Early Child Development” on March 10.
Mary Beth Bollinger, DO, Associate Professor, Department of Pediatrics, presented “The Asthma Pendulum: Development of Asthma and Progression of Atopic Disease” at the American Academy of Allergy, Asthma and Immunology Annual Meeting in Atlanta in early March.
Natalie Davis, MD, MMSc, Assistant Professor, Department of Pediatrics, was the 2017 invited speaker for the annual “Let’s Talk” Webinar/Teleconference presented by the American Academy of Pediatrics Traffic Injury Prevention Project (Pennsylvania Chapter). She presented “Who, What, When, Where, Why, and How of the Car Seat Tolerance Test” to over 300 participants.
Colleen Hughes Driscoll, MD, Assistant Professor, Department of Pediatrics, presented “Using Wireless Text Messaging for Communication During Neonatal Resuscitation Events” at the 2017 Health Information and Management Systems Society Conference in Orlando, FL on February 22.
Mangla Gulati, MD, FACP, SFHM, Assistant Professor, Department of Medicine, presented “To Err is Human: Decreasing Medical Errors In the Hospital – and Human Factor Engineering” at the American College of Physicians Internal Medicine Meeting, held in San Diego in March.
Ellen Higginson, PhD, Postdoctoral Fellow, Center for Vaccine Development and the Institute for Global Health, presented “Virulence of Invasive Salmonella Typhimurium ST313 in Animal Infection Models” at the 10th International Conference on Typhoid and Other Invasive Salmonelloses in Kampala, Uganda on April 6.
Stella Hines, MD, MSPH, Assistant Professor, Department of Medicine, was invited to present “Metals and Interstitial Lung Disease” at the American Academy of Asthma, Allergy and Immunology meeting on March 4 in Atlanta.
Irene Kasumba, PhD, Postdoctoral Fellow, Center for Vaccine Development and the Institute for Global Health, presented “Salmonella enterica Serovars Isolated from Stool of Children Enrolled in the Global Enteric Multicenter Study in Africa” at the 10th International Conference on Typhoid and Other Invasive Salmonelloses in Kampala, Uganda on April 6.
Miriam Laufer, MD, MPH, Associate Professor of Pediatrics and Director, Division of Malaria Research, Institute for Global Health, presented the Frontier Lecture in Infectious Diseases entitled “Using Science to Defeat Malaria in Sub-Saharan Africa” at the 16th Annual St. Jude’s Pediatric Infectious Diseases Research Conference. Dr. Laufer also participated in the career pathways panel discussion to talk about careers in global health.
Myron Levine, MD, DTPH, the Simon and Bessie Grollman Distinguished Professor of Medicine and Associate Dean for Global Health, Vaccinology and Infectious Diseases, Institute for Global Health, presented “A Broad-Spectrum Vaccine to Prevent Invasive Salmonella Disease in Sub-Saharan Africa” at the 10th International Conference on Typhoid and Other Invasive Salmonelloses in Kampala, Uganda on April 5.
Philip Mackowiak, MD, MACP, Professor Emeritus in the Department of Medicine and the Carolyn Frenkil and Selvin Passen History of Medicine Scholar-in-Residence, was the Eighth Annual George A. Sarosi Visiting Professor at the Indiana University School of Medicine on March 16 & 17. He also was Visiting Professor at the Institute for Lifelong Learning at Susquehanna University in Selinsgrove, PA, in late March.
Sandra Mooney, PhD, Associate Professor, Department of Pediatrics presented “Prenatal Ethanol Exposure Induces Deficits in Cognitive Function in Adulthood; Improvement with Choline and Behavior Training” at the 7th International Conference on Fetal Alcohol Spectrum Disorder held in Vancouver, Canada, in early March.
Kathleen Neuzil, MD, MPH, FIDSA, Professor of Medicine and Director, Center for Vaccine Development, moderated a session entitled “Global Trends in Typhoid Fever: Determinants and Implications for Policy” at the 10th International Conference on Typhoid and Other Invasive Salmonelloses in Kampala, Uganda, on April 5. She also presented “Introduction of Typhoid Conjugate Vaccines: Opportunities and Challenges” at the same meeting on April 6.
Ada Offurum, MD, Assistant Professor, Department of Medicine, presented “Update on Venous Thrombo-Embolic Disease” at the American College of Physician Annual Maryland Winter Scientific Meeting, held February 17 & 18 at Turf Valley Resort in Ellicott City, MD. Dr. Offurum and Mangla Gulati, MD, FACP, SFHM, Assistant Professor, Department of Medicine, facilitated the “Hospital Maintenance of Certification” Session for the American Board of Internal Medicine at the same meeting.
Michelle Pearce, PhD, Assistant Professor, Department of Family and Community Medicine, will direct a new, 12-credit online graduate certificate in Integrative Health and Wellness in the Graduate School. In this one-year program, students will learn the fundamental concepts, philosophies, and methods of integrative health, as well as analyze empirical research on the use, benefits, and effects of integrative approaches to healing. Notably, beyond studying the research, participants will have the opportunity to experience and practice integrative mind-body interventions and key health coaching skills. This experiential learning is designed to contribute to both professional and personal development. Finally, participants will learn how to apply their knowledge of integrative health and wellness to assessment and treatment planning. To learn more about the program, visit graduate.umaryland.edu/wellness.
Ken Simiyu, PhD, Senior Program Director, Center for Vaccine Development and the Institute for Global Health, moderated a session entitled “Crush the Resistance: Antimicrobial Resistance Session” at the 10th International Conference on Typhoid and Other Invasive Salmonelloses in Kampala, Uganda on April 5.
Rafael Simon, PhD, Assistant Professor of Medicine, Center for Vaccine Development and the Institute for Global Health, presented “S. Typhimurium Core-OPS (COPS) Glycoconjugate with the Homologous Serovar Phase 1 Flagellin as a Vaccine to Prevent Invasive S. Typhimurium Infections in Sub-Saharan Africa” at the 10th International Conference on Typhoid and Other Invasive Salmonelloses in Kampala, Uganda on April 5.
Douglas Sward, MD, Clinical Assistant Professor, Department of Emergency Medicine, presented a workshop during the Wilderness and Disaster Medicine course at the University of Pennsylvania Perelman School of Medicine in early March. Titled “Search and Rescue: Initial Tasks and Reflex Actions,” his didactic presentation reviewed lost person behavior and its application to search strategies and was followed by a hands-on exercise that asked students to develop a search strategy using a topographic map. The two-week course encourages students to improvise under austere conditions and prepares them to respond to emergencies in wilderness settings as well as disaster scenarios. A Wall Street Journal article about the course can be found at https://www.wsj.com/articles/latest-medical-school-trend-wilderness-training-1490097604?emailToken=JRryd/96aHqXgdY1b8w43UEldbVNDuKFR1jeKDXRMUjLs3iQvfiswalwmNqzrW61Q0th/JUY9Wc+QzzXjy8zAJ7Jw+8gzw/4.
Marcelo Sztein, MD, Professor of Medicine, Center for Vaccine Development and the Institute for Global Health, presented “Recent Advances in the Identification of Immunological Correlates of Protection in a Human S. Typhi Challenge Model” at the 10th International Conference on Typhoid and Other Invasive Salmonelloses in Kampala, Uganda on April 6.
Rezwanul Wahid, MBBS, PhD, Assistant Professor of Medicine, Center for Vaccine Development and the Institute for Global Health, presented “Live Oral Typhoid Vaccine Ty21a Elicited Cross-Reactive Multifunctional IL-17A Producing T Cell Responses Against Salmonella enterica Serovars in Humans” and “Cell-Mediated Immune Response Elicited in Volunteers Immunized with the Novel Live Oral Salmonella enterica Serovar Paratyphi A Vaccine Strain CVD1902” at the 10th International Conference on Typhoid and Other Invasive Salmonelloses in Kampala, Uganda on April 4.
Neuroimaging Retreat Once Again a Great Success
The Maryland Neuroimaging Retreat was held on April 14 at the University of Maryland, Baltimore with over one hundred people in attendance. The annual event drew neuroimaging researchers, postdocs, and students from the Baltimore-Washington area to hear presentations from experts in the field of brain research and to engage in panel discussions. The theme of this year’s program was Pain Neuroimaging: Advances and Controversies, and featured 11 regional, national, and international speakers. Members of the organizing committee included Rao Gullapalli, PhD, Professor and Shiyu Tang, Research Assistant, both from the Department of Diagnostic Radiology & Nuclear Medicine, and David Seminowicz, PhD, Associate Professor, and Joel Greenspan, PhD, Professor and Chair, both from the Department of Neural and Pain Sciences in the School of Dentistry.
Congratulations to the following who have received honors!
Sandra Quezada, MD, MS, Assistant Professor, Department of Medicine, and Assistant Dean for Admissions, received the Inaugural Dean’s Alumni Award for Diversity and Inclusion, which was given at the “Celebrating Diversity” Dinner on February 25.
Kenneth Robinson, MD, Assistant Professor, Department of Anesthesiology, was recognized as one of the 2017 40 Under 40 Leaders in Minority Health by the National Minority Quality Forum Leadership Summit on Health Disparities. The award was presented at the Congressional Black Caucus Health Braintrust Awards gala dinner on April 25.
Areck Ucuzian, MD, PhD, Assistant Professor of Surgery, Center for Vascular and Inflammatory Diseases, has been chosen as the winner of the 2017 Robert W. Hobson, II, MD Early Career Investigator Award for his abstract “Deletion of LRP1 in SMCs Differentially Alters Susceptibility of Distinct Vascular Beds to BAPN-induced Aneurysm and Dissection Formation.” The Robert W. Hobson, II, MD Early Career Investigator Award is sponsored by the Council on Peripheral Vascular Disease, American Heart Association. This award recognizes excellence in basic or clinical science in early career investigators in vascular and endovascular medicine, vascular surgery, or vascular biology. Dr. Ucuzian’s awarded study was to investigate the role of smooth muscle cell LDL receptor-related protein 1 (LRP1) in modulating the susceptibility of various vascular beds to chemically induced dissections and aneurysms in an animal model.
University of Maryland School of Medicine Translational Genomics Laboratory Receives Accreditation from College of American Pathologists
The College of American Pathologists (CAP) has awarded accreditation to the University of Maryland School of Medicine’s (UMSOM) Translational Genomics Laboratory (TGL) based on results of a recent on-site inspection as part of the CAP’s Accreditation Programs.
The facility’s laboratory director, Linda Jeng, MD, PhD was advised of this national recognition and congratulated for the excellence of the services being provided. In addition to the TGL director, the quality assurance manager, Danielle Sewell, played an integral role in the accreditation process and successful inspection and the technical supervisor, Nicholas Ambulos, PhD, is instrumental in developing the TGL. The TGL is one of more than 7,600 CAP-accredited facilities worldwide. The U.S. federal government recognizes the CAP Laboratory Accreditation Program, begun in the early 1960s, as being equal-to or more-stringent-than the government’s own inspection program.
During the CAP accreditation process, designed to ensure the highest standard of care for all laboratory patients, inspectors examine the laboratory’s records and quality control of procedures for the preceding two years. CAP inspectors also examine laboratory staff qualifications, equipment, facilities, safety program and record, and overall management.
The TGL is part of the School of Medicine’s Program for Personalized and Genomic Medicine (PPGM) and the Center for Innovative Biomedical Resources (CIBR). Alan Shuldiner, MD, the John A. Whitehurst Professor of Medicine and director of the PPGM, established the PPGM to advance discovery in genomics and other “omics” sciences, accelerate translational research, and implement these discoveries into more effective and safe individualized health care. Nicholas Ambulos, PhD, director of CIBR, established CIBR to provide specialized expertise, cutting-edge technologies and sophisticated scientific resources supporting a robust basic, clinical and translational biomedical research environment at UMBSOM. The TGL was developed as a critical bridge to help accelerate translation from discovery into precision health care, providing DNA sequencing, genotyping and array-based technologies. These resources place UMSOM in the extraordinary position of providing its faculty with the comprehensive tools to support genomic studies from discover through implementation into clinical care.
About the College of American Pathologists
The College of American Pathologists (CAP), celebrating 50 years as the gold standard in laboratory accreditation, is a medical society that serves more than 18,000 physician members and the global laboratory community. It is the world’s largest association composed exclusively of board-certified pathologists and is the worldwide leader in laboratory quality assurance. The College advocates accountable, high-quality, and cost-effective patient care. More information about the CAP can be found at www.cap.org.
We applaud our colleagues on their recent appointments!
Maureen Black, PhD, the John A. Scholl, MD and Mary Louise Scholl, MD Professor in Pediatrics, has been invited to serve a four-year term (2017-2021) as a regular member of the Psychosocial Development, Risk and Prevention Study Section at the National Institutes of Health (NIH).
Christopher Plowe, MD, MPH, FASTMH, the Frank M. Calia MD Professor of Medicine and Founding Director, Institute for Global Health, was appointed to the editorial board of the Myanmar Health Sciences Research Journal.
Niharika Khanna, MBBS, MD, DGO, Associate Professor, Department of Family & Community Medicine, and Director of the Maryland Learning Collaborative, has been selected as Co-Chair of the DHMH Maryland Cancer Collaborative HPV Workgroup.
Congratulations to our very productive faculty on their recent grants and contracts!
Andrea Berry, MD, Assistant Professor of Pediatrics, Institute for Global Health, received a five-year, $915,020 NIH Mentored Patient-Oriented Research Career Development Award for “Protein Microarray Antibody Responses to P. falciparum in a Human Challenge Model.” Dr. Berry also entered into a Clinical Study Agreement with Corixa Corporation, a member of the GSK Companies, for the protocol “A Phase 1/2, Randomized, Observer-Blind, Controlled, Multi-Center, Dose-Escalation Study to Evaluate Safety, Reactogenicity and Immunogenicity of GSK Biologicals’ Respiratory Syncytial Virus (RSV) Investigational Vaccine Based on the RSV Viral Proteins F, N and M2-1 Encoded by Chimpanzee-Derived Adenovector (Chad155-RSV) (GSK3389245A), When Administered Intramuscularly According to a 0, 1-Month Schedule to RSV-Sseropositive Infants Aged 6 to 17 Months.”
James Campbell, MD, MS, Professor of Pediatrics, Center for Vaccine Development (CVD) and the Institute for Global Health, received a six-year, $7,592,089 award to design and perform the clinical trial and laboratory assays for the protocol “Phase 4 Trial to Evaluate the Efficacy of an Injectable-Free (All Oral) Delamanid-Containing Regimen for the Treatment of Multidrug-Resistant Pulmonary Tuberculosis.” This is part of the NIAID contract awarded to Karen Kotloff, MD, Professor of Pediatrics, for a Vaccine Treatment and Evaluation Unit within CVD.
Wilber Chen, MD, MS, Associate Professor of Medicine, Center for Vaccine Development and the Institute for Global Health, has entered into a Research Services Agreement with the American Cleaning Institute. Dr. Chen will advise ACI on matters related to the development of clinical efficacy studies to evaluate OTC topical antiseptic hand products and will draft a proposal for testing whether antibacterial active ingredients reduce the risk of infection in a human challenge model using enterotoxigenic E. coli.
Curt Civin, MD, Associate Dean for Research; Director, Center for Stem Cell Biology & Regenerative Medicine; and Professor of Pediatrics and Physiology, received a subcontract from the University of Maryland, College Park (UMCP) to participate and advise on stem cell and molecular biology in the new NIH P41-funded “Center for Engineering Complex Tissues” (CECT; PI: John Fisher PhD, Chair, Department of BioEngineering, UMCP). Total five-year funding for the Center is $6,302,200. Collaborators also include Rice University and Wake Forest Institute for Regenerative Medicine. CECT will oversee six collaborative projects, six service projects, and multiple training programs to foster expert collaborations for the advancement of tissue engineering.
Eduardo Davila, PhD, Associate Professor, Department of Microbiology & Immunology, received a five-year, $363,833 grant from the National Cancer Institute of the National Institutes of Health for “Augmenting T-cell Activity to Weak Tumor Antigens and Reversing Myeloid Cell-Mediated T-cell Inhibition.
Mao Fu, PhD, Assistant Professor of Medicine, Program in Personalized and Genomic Medicine, received a two-year, $154,000 grant from the American Heart Association (AHA) for “Functional Genetic Variants for Lipoprotein (a) Levels.”
Shannon Takala Harrison, PhD, Associate Professor of Medicine, Institute for Global Health, received a five-year, $1,632,515 NIH R01 award for “Identification and Validation of Molecular Markers of Piperaquine Resistance.”
Kirsten Lyke, MD, Associate Professor of Medicine, Institute for Global Health, received a $1.17 million grant from The Geneva Foundation for “A Phase I, Randomized, Placebo-Controlled Trial to Assess the Safety, Reactogenicity and Immunogeneicity of a Combination HTNV and PUUV Virus DNA Vaccine Candidate Administered by Electroporation.”
Jeffrey O’Connell, PhD, Associate Professor of Medicine, Program in Personalized and Genomic Medicine, received a three-year, $1.7 million U01 grant from the National Heart, Lung, And Blood Institute (NHLBI) for “High-Performance Mixed Model Toolset for Integrative Omics Analysis of Big Data.”
Christopher Plowe, MD, MPH, FASTMH, the Frank M. Calia MD Professor of Medicine and Founding Director, Institute for Global Health, and Myaing Nyunt, MD, MPH, PhD, Assistant Professor of Medicine, Institute for Global Health, received a seven-year, $9,176,772 U19 Award from NIAID for “Myanmar Regional Center of Excellence for Malaria Research.” The current year award is for $1,395,966.
Taehoon Shin, PhD, Assistant Professor, Department of Diagnostic Radiology & Nuclear Medicine, was awarded a four year, $1.5 million R01 grant from the National Heart, Lung and Blood Institute for “Non-Contrast-Enhanced Peripheral MR Angiography.” One of Dr. Shin’s primary research interests is unenhanced angiography, which is considered a highly promising approach to visualize arteries because of the absence of side effects of ionizing radiation from CTA and nephrogenic systemic fibrosis from gadolinium-enhanced MRA. At the core of the method is velocity-selective (VS) excitation pulse which excites magnetic spins based on their velocities but independently of their spatial location in a way that highlights rapidly moving arterial blood while suppressing venous blood and relatively stationary tissues such as muscle. Dr. Shin’s research involves clinical collaboration with Robert Crawford, MD, Associate Professor, Departments of Surgery and Anesthesiology, and Dheeraj Gandhi, MBBS, Professor, Department of Diagnostic Radiology & Nuclear Medicine, both experts in clinical vascular imaging. While the awarded grant focuses specifically on peripheral angiography, the proposed technique can be easily adapted for other arterial territories such as cerebral, renal and pedal. In addition to angiography applications, VS excitation schemes will be highly applicable to other areas of MR development including ASL perfusion, vessel wall imaging and venography.
Mark Travassos, MD, MSc, Assistant Professor of Pediatrics, Institute for Global Health, received a two-year, $75,000 Clinical-Investigator Award for Career Development from the Passano Foundation for “Understanding Mechanisms Underlying Acquired Protective Immunity to Cerebral Malaria.”
Hats off to those who have been published!
Samson Assefa, MD, Assistant Professor; Montserrat Diaz-Abad, MD, Assistant Professor; and Steven Scharf, MD, Professor, all from Department of Medicine, co-authored “Sleep Apnea—Recent Updates” in the online Open Access journal InTech on Apr 5.
Eileen Barry, PhD, Professor of Medicine, Center for Vaccine Development and the Institute for Global Health, was among the co-authors on “Analysis of Shigella Flexneri Resistance, Biofilm Formation, and Transcriptional Profile in Response to Bile Salts” in Infection and Immunity, 2017 Mar 27 [Epub ahead of print].
Andrea Berry, MD, Assistant Professor of Pediatrics, Institute for Global Health, was the senior author on “Two-Year Antibody Persistence in Children Vaccinated at 12-15 Months with a Measles-Mumps-Rubella Virus Vaccine Without Human Serum Albumin” in Human Vaccines & Immunotherapeutics, 2017;13(7).
Maureen Black, PhD, the John A. Scholl, MD and Mary Louise Scholl, MD Professor in Pediatrics, published a chapter entitled “Prevention: A Multi-Level, Bio-Behavioral, Lifespan Perspective” in The Handbook of Pediatric Psychology, and a chapter entitled “Responsive Feeding: Strategies to Promote Healthy Mealtime Interaction” in the Nestle Nutrition Institute Workshop Series.
Uttam Bodanapally, MBBS, Assistant Professor; David Dreizin, MD, Assistant Professor; Krystal Archer-Arroyo, MD, Assistant Professor; and Babak Saboury, MD, Third-year Resident, all from the Department of Diagnostic Radiology & Nuclear Medicine, were among the co-authors on “Prognostic Predictors of Visual Outcome in Open Globe Injury: Emphasis on Facial CT Findings” in AJNR–American Journal of Neuroradiology, 2017 Mar 16 [Epub ahead of print].
Mary Beth Bollinger, DO, Associate Professor, Department of Pediatrics was among the co-authors on “Effect of an Integrated Pest Management Intervention on Asthma Symptoms Among Mouse-Sensitized Children and Adolescents with Asthma: A Randomized Clinical Trial” in JAMA, 2017 Mar 6 [Epub ahead of print].
Laura Bontempo, MD, MEd, Assistant Professor, Department of Emergency Medicine, published “Family Medical History” in the Reflections column of Academic Emergency Medicine, 2017 Feb 24(2):254–255. In this pensive essay, Dr. Bontempo examined the impact of a question asked by many practitioners during their initial assessment of a patient. Routine inquiry into the family’s medical history is much less routine when seen from the patient’s point of view.
Rong Chen, PhD, Assistant Professor; Edward Herskovits, MD, Professor; and Elias Melhem, MD, PhD, Professor and the Dean John M. Dennis Chairman, all from the Department of Diagnostic Radiology & Nuclear Medicine were among the co-authors on “Brain Morphometric Analysis Predicts Decline of Intelligence Quotient in Children with Sickle Cell Disease: A Preliminary Study” in Advanced Medical Science, 2017 Mar 6;62(1):151-157.
Kunrong Cheng, PhD, Assistant Professor, and Jean-Pierre Raufman, MD, Professor, both from the Department of Medicine; Cinthia Drachenberg, MD, Professor, Department of Pathology; and Min Zhan, PhD, Associate Professor, Department of Epidemiology & Public Health, were among the co-authors on “Differential Expression of M3 Muscarinic Receptors in Progressive Colon Neoplasia and Metastasis” in Oncotarget, 2017 Mar 28;8(13):21106-21114.
Nina Connolly, PhD, Postdoctoral Fellow; Anthony Kim, PhD, Assistant Professor; J Marc Simard, MD, PhD, Professor; and Graeme Woodworth, MD, Associate Professor, all from the Department of Neurosurgery; Su Xu, PhD, Associate Professor, Department of Diagnostic Radiology & Nuclear Medicine; Rudolph Castellani, MD, Clinical Professor, Department of Pathology; and Jeffrey Winkles, PhD, Professor, Department of Surgery were among the co-authors on “Genetically Engineered Rat Gliomas: PDGF-Driven Tumor Initiation and Progression in Tv-A Transgenic Rats Recreate Key Features of Human Brain Cancer” in PLoS One, 2017 Mar 30;12(3):e0174557 (eCollection 2017).
Vasken Dilsizian, MD, Professor, Department of Diagnostic Radiology & Nuclear Medicine, was the corresponding author on “Myocardial Viability: Survival Mechanisms and Molecular Imaging Targets in Acute and Chronic Ischemia” in Circulation Research, 2017;120:1197-1212.
David Dreizin, MD, Assistant Professor, and Nikki Tirada, MD, Assistant Professor, both from the Department of Diagnostic Radiology & Nuclear Medicine, were among the co-authors on “Abdominal and Pelvic Trauma: Misses and Misinterpretations at Multidetector CT: Trauma/Emergency Radiology” in Radiographics, 2017 Mar-Apr;37(2):703-704.
Stephanie Fresnay, PhD, Postdoctoral Fellow; Myron Levine, MD, DTPH, the Simon and Bessie Grollman Distinguished Professor of Medicine and Associate Dean for Global Health, Vaccinology and Infectious Diseases; and Marcelo Sztein, MD, Professor of Medicine, all from the Center for Vaccine Development and the Institute for Global Health, were among the co-authors on “Challenge of Humans with Wild-type Salmonella Enterica Serovar Typhi Elicits Changes in the Activation and Homing Characteristics of Mucosal-Associated Invariant T Cells” in Frontiers in Immunology, 2017 Apr 6;8:398 [eCollection 2017]. Drs. Fresnay, Levine and Sztein, along with Monica McArthur, MD, PhD, Assistant Professor, were among the co-authors on “Importance of Salmonella Typhi-responsive CD8+ T Cell Immunity in a Human Typhoid Fever Challenge Model” in Frontiers in Immunology, 2017 Mar 2;8:208.
Stella Hines, MD, MSPH, Assistant Professor, Department of Medicine; Van Kim Holden, MD, Clinical Fellow, Division of Pulmonary & Critical Care Medicine; and Seth Kligerman, MD, Associate Professor, Department of Diagnostic Radiology & Nuclear Medicine, were among the co-authors on “Unabated Occupational Risk in a Patient with Rheumatoid Pulmonary Fibrosis” in Occupational Medicine, 2017 Feb 23 [Epub ahead of print].
Jason Hostetter, MD, Fourth-year Resident; Michael Morris, MD, Third-year Resident; Jean Jeudy, MD, Associate Professor; and Eliot Siegel, MD, Professor, all from the Department of Diagnostic Radiology & Nuclear Medicine, were among the co-authors on “Personalizing Lung Cancer Risk Prediction and Imaging Follow-Up Recommendations Using the National Lung Screening Trial Dataset” in Journal of the American Medical Informatics Association (JAMIA), 2017 Mar 10 [Epub ahead of print]. Dr. Siegel was also a co-author on “A Patient as Art: Andrew Wyeth’s Portrayal of Christina Olson’s Neurologic Disorder in Christina’s World” in Journal of Child Neurology, 2017 Jan 1:883073817700603 [Epub ahead of print], and “Oliver Cromwell’s Fatal Ague” in The American Journal of the Medical Sciences, 2017 Apr;353(4):398-401.
Jon Mark Hirshon, MD, MPH, PhD, Professor, Departments of Emergency Medicine and Epidemiology and Public Health, as a member of the Clinical Policies Committee of the American College of Emergency Physicians, contributed to the organization’s new policy on the diagnosis and management of adult psychiatric patients in emergency departments. The policy was published in Annals of Emergency Medicine, 2017 Apr;69(4):480–498.
Jane Kim, MD, Assistant Professor, and Narendra Shet, MD, Assistant Professor, both from the Department of Diagnostic Radiology & Nuclear Medicine, were among the co-authors on “Postnatal MRI for CDH: A Pictorial Review of Late-Presenting and Recurrent Diaphragmatic Defects” in Clinical Imaging, 2017 Mar 8;43:158-164.
Seth Kligerman, MD, Assistant Professor, Department of Diagnostic Radiology & Nuclear Medicine, was among the co-authors on “Unabated Occupational Risk in a Patient with Rheumatoid Pulmonary Fibrosis” in Occupational Medicine (London), 2017 Feb 23 [Epub ahead of print].
Kathleen Neuzil, MD, MPH, FIDSA, Professor of Medicine and Director, Center for Vaccine Development, was among the co-authors on “Effectiveness of a Live Oral Human Rotavirus Vaccine After Programmatic Introduction in Bangladesh: A Cluster-Randomized Trial” in PLOS Medicine, 2017 Apr 18;14(4):e1002282. She also was among the co-authors on “Cystic Fibrosis Pulmonary Exacerbations Attributable to Respiratory Syncytial Virus and Influenza: A Population-based Study” in Clinical Infectious Diseases, 2017 Mar 9 [Epub ahead of print].
Aruna Panda, BVSc, PhD, MPH, Associate Professor of Pathology and Epidemiology & Public Health, Program of Comparative Medicine; Louis DeTolla, VMD, PhD, DACLAM, Professor of Pathology, Medicine, and Epidemiology & Public Health and Director, Program of Comparative Medicine; and Hervé Tettelin, PhD, Associate Professor of Microbiology & Immunology, Institute for Genomic Sciences, were among the co-authors on “Complete Genome Sequences of Mycobacterium kansasii Strains Isolated from Rhesus Macaques” in Genome Announcements, 2017 Apr 20;5(16).
Marcela Pasetti, PhD, Professor of Pediatrics, Center for Vaccine Development and the Institute for Global Health, was among the co-authors on “A Primary Human Macrophage-Enteroid Co-culture Model to Investigate Mucosal Gut Physiology and Host-Pathogen Interactions” in Scientific Reports, 2017 Mar 27;7:45270.
Brian Polster, PhD, Associate Professor, Department of Anesthesiology, was corresponding author on “The Putative Drp1 Inhibitor Mdivi-1 is a Reversible Complex I Inhibitor that Modulates Reactive Oxygen Species” in Developmental Cell, 2017 Mar 27;40(6):583-594.e6.
Horea Rus, MD, PhD, Professor, Department of Neurology; Alexandru Tatomir, PhD, Postdoctoral Fellow, Department of Neurology; Daniel Hewes, MS III; Jonathan Ciriello, MS II; and Adam Kruszewski, MS IV, were among the co-authors on “SIRT1 as a Potential Biomarker of Response to Treatment with Glatiramer Acetate in Multiple Sclerosis” in Experimental and Molecular Pathology, 2017, 102: 191-197. Daniel and Adam were both recipients of a Medical Student Research Scholarship Award from the Foundation of the Consortium of Multiple Sclerosis Centers.
Randall Schultz, MD, Fellow; Andrew Steven, MD, Assistant Professor; Dheeraj Gandhi, MBBS, Professor; and Prashant Raghavan, MD, Associate Professor, all from the Department of Diagnostic Radiology & Nuclear Medicine, along with Charles Sansur, MD, FAANS, Associate Professor, and David Ibrahimi, MD, Assistant Professor, both from the Department of Neurosurgery, were among the co-authors on “Differentiation of Idiopathic Spinal Cord Herniation from Dorsal Arachnoid Webs on MRI and CT Myelography” in Journal of Neurosurgery. Spine, 2017 Mar 24:1-6 [Epub ahead of print].
Mohsin Shahzad, PhD, Postdoctoral Fellow (first author); Sairah Yousaf, MSc, Graduate Student (co-first author); Saima Riazuddin, PhD, MPH, Professor; and Zubair Ahmed, PhD, Professor, all from the Department of Otorhinolaryngology–Head and Neck Surgery, were among the co-authors on “Molecular Outcomes, Clinical Consequences, and Genetic Diagnosis of Oculocutaneous Albinism in Pakistani Population” in Scientific Reports, 2017 Mar 7;7:44185. Dr. Ahmed was also among the co-authors on “Benign Yellow Dot Maculopathy: A New Macular Phenotype” in Ophthalmology, 2017 Mar 30;S0161-6420(16)32160-1.
Kathirkama Shanmuganathan, MBBS, Professor; Jiachen Zhuo, PhD, Assistant Professor; Rao Gullapalli, PhD, MBA, Professor; and Stuart Mirvis, MD, Professor, all from the Department of Diagnostic Radiology & Nuclear Medicine, were among the co-authors on “Diffusion Tensor Imaging Parameter Obtained During Acute Blunt Cervical Spinal Cord Injury in Predicting Long Term Outcome” in Journal of Neurotrauma, 2017 Apr 6 [Epub ahead of print].
Shiyu Tang, Research Assistant; Su Xu, PhD, Associate Professor; and Rao Gullapalli, PhD, MBA, Professor, all from the Department of Diagnostic Radiology & Nuclear Medicine, were among the co-authors on “Central Nervous System Changes Induced by Underbody Blast-Induced Hyperacceleration: An in Vivo Diffusion Tensor Imaging and Magnetic Resonance Spectroscopy Study” in Journal of Neurotrauma, 2017 Mar 21 [Epub ahead of print]. Dr. Gullapalli, along with Steven Roys, MS, Research Associate, Department of Diagnostic Radiology & Nuclear Medicine, was among the co-authors on “Predictors and Brain Connectivity Changes Associated with Arm Motor Function Improvement from Intensive Practice in Chronic Stroke” in Version 2. F1000Res, 2016 Aug 31 [revised 2017 Feb 28];5:2119.
Milagritos Tapia, MD, Associate Professor of Pediatrics; Samba Sow, MD, MS, Adjunct Professor of Medicine; Sharon Tennant, PhD, Assistant Professor of Medicine; Myron Levine, MD, DTPH, the Simon and Bessie Grollman Distinguished Professor of Medicine and Associate Dean for Global Health, Vaccinology and Infectious Diseases, all from the Center for Vaccine Development and the Institute for Global Health, were among the co-authors on “Distinct Salmonella Enteritidis Lineages Associated with Enterocolitis in High-Income Settings and Invasive Disease in Low-Income Settings” in Nature Genetics, 2017 March 30;49(4):651.
Stephen Thom, MD, PhD, Professor; Veena Bhopale, MPhil, PhD, Lab Manager; JingPing Hu, PhD, Research Specialist; and Ming Yang, MD, Research Associate, all from the Department of Emergency Medicine, co-authored “Increased Carbon Dioxide Levels Stimulate Neutrophils to Produce Microparticles and Activate the Nucleotide-Binding Domain-Like Receptor 3 Inflammasome” in Free Radical Biology and Medicine, 2017 May;106:406–416.
Charles White, MD, Professor, Department of Diagnostic Radiology & Nuclear Medicine, was last author on “Diagnosis of Grave’s Disease with Pulmonary Hypertension on Chest CT” in Clinical Imaging, 2017 Mar 23;43:188-193.
R. Gentry Wilkerson, MD, Assistant Professor, Department of Emergency Medicine, and Omoyemi Adebayo, MD, a 2015 graduate of the Emergency Medicine residency, were co-authors on “Angiotensin-Converting Enzyme Inhibitor-Induced Angioedema Worsened with Fresh Frozen Plasma” in The American Journal of Emergency Medicine, 2017 Jan;35(1):192.e1–192.e2.
Jeffrey Wolf, MD, Associate Professor, and Amal Isaiah, MD, Assistant Professor, both from the Department of Otorhinolaryngology–Head and Neck Surgery, and Reuben Mezrich, MD, PhD, Professor, Department of Diagnostic Radiology & Nuclear Medicine, were the co-authors on “Ultrasonographic Detection of Airway Obstruction in a Model of Obstructive Sleep Apnea” in Ultrasound International Open, 2017 Feb;3(1):E34-E42.
Junfang Wu, BM, PhD, Associate Professor, and Alan Faden, MD, the David S. Brown Professor in Trauma and Director of the Shock, Trauma & Anesthesiology Research (STAR) Center, were among the co-authors on “Truncated TrkB.T1-Mediated Astrocytes Dysfunction Contributes to Impaired Motor Function and Neuropathic Pain After Spinal Cord Injury” in Journal of Neuroscience, 2017 Apr 5;37(14):3956-3971.
Su Xu, PhD, Associate Professor, Department of Diagnostic Radiology & Nuclear Medicine, was among the co-authors on “Genetically Engineered Rat Gliomas: PDGF-Driven Tumor Initiation and Progression in tv-a Transgenic Rats Recreate Key Features of Human Brain Cancer” in PLoS One, 2017 Mar 30;12(3):e0174557 [eCollection 2017].